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PAIRB rabbit pAb

CAT: 0855-ES10010-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10010-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay., subcellular location:Also found in perinuclear regions., subunit:Interacts with CHD3 and TDRD3., tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
Description
Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. subcellular location: Also found in perinuclear regions. subunit: Interacts with CHD3 and TDRD3. tissue specificity: Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
UniProt
Q8NC51
Swiss Prot
Q8NC51
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 60-140
Target
PAIRB
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
44kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
44kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, perinuclear region .
Gene ID (Human)
26135

UniProtKB · Q8NC51

SERPINE1 mRNA-binding protein 1

SERB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NC51
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERBP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5VU19, Q5VU20, Q5VU22, Q8WUH0, Q96SE2, Q9BTY3, Q9BUM4, Q9Y367, Q9Y4S3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

RNA-binding

Biological process

Translation regulation

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