NGDN rabbit pAb

• Background:

  Neuroguidin is an EIF4E (MIM 133440) -binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]) .[supplied by OMIM, Mar 2008]

• Description:

  Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al. 2006 [PubMed 16705177]). [supplied by OMIM, Mar 2008],

• Gene ID:

  25983

• UniProt:

  Q8NEJ9

• Cellular Locus:

  Nucleus. Nucleus, nucleolus. Chromosome, centromere. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Cell projection, filopodium. Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 240-320

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  34kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  34 kD

• Subcellular Location:

  Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity) . Translocated from nucleolus to nuclear foci in response to UV damage. .

• Gene ID (Human):

  25983

• SwissProt (Human):

  Q8NEJ9