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UNC5B rabbit pAb

CAT: 0855-ES9891-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9891-01Size:50 µL
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Background
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
Description
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
UniProt
Q8IZJ1
Swiss Prot
Q8IZJ1
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 350-430
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
103kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
103kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Membrane raft . Associated with lipid rafts. .
Gene ID (Human)
219699

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