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UNC5C rabbit pAb

CAT: 0855-ES9892-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES9892-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]
Description
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008],
UniProt
O95185
Swiss Prot
O95185
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 60-140
Target
UNC5C
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
102kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
102kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cell surface . Cell junction, synapse, synaptosome . Cell projection, axon . Cell projection, dendrite . Cell projection, growth cone . Cell projection, lamellipodium . Cell projection, filopodium .
Gene ID (Human)
8633

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