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LTOR2 rabbit pAb

CAT: 0855-ES9208-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9208-02Size:100 µL
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Background
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Description
The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],
UniProt
Q9Y2Q5
Swiss Prot
Q9Y2Q5
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Target
LTOR2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
13kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
13kD
Fragment
IgG
Subcellular Location
Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
Gene ID (Human)
28956

UniProtKB · Q9Y2Q5

Ragulator complex protein LAMTOR2

LTOR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y2Q5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMTOR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5VY97, Q5VY98, Q5VY99
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

EndosomeLysosomeMembrane

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