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EPS8 rabbit pAb

CAT: 0855-ES9052-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9052-01Size:50 µL
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Background
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],
UniProt
Q12929
Swiss Prot
Q12929
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
90kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
90kD
Fragment
IgG
Subcellular Location
Cytoplasm, cell cortex . Cell projection, ruffle membrane . Cell projection, growth cone . Cell projection, stereocilium . Cell junction, synapse, synaptosome . Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity) . Localizes to the midzone of dividing cells. .
Gene ID (Human)
2059

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