EPS8 rabbit pAb

• Background:

  This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],

• UniProt:

  Q12929

• Swiss Prot:

  Q12929

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 130-210

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  90kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  90kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, cell cortex . Cell projection, ruffle membrane . Cell projection, growth cone . Cell projection, stereocilium . Cell junction, synapse, synaptosome . Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity) . Localizes to the midzone of dividing cells. .

• Gene ID (Human):

  2059