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EFNB2 rabbit pAb

CAT: 0855-ES9042-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9042-02Size:100 µL
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Background
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008],
UniProt
P52799
Swiss Prot
P52799
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
Target
EFNB2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
36kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cell junction, adherens junction .
Gene ID (Human)
1948

UniProtKB · P52799

Ephrin-B2

EFNB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52799
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EFNB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5JV56
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

AngiogenesisDifferentiationHost-virus interactionNeurogenesis

Cellular component

Cell junctionCell membraneMembrane

Molecular function

Developmental proteinHost cell receptor for virus entryReceptor

PTM

Disulfide bondGlycoproteinMethylationPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

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