FA2H rabbit pAb

• Background :

  This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.[provided by RefSeq, Mar 2010]

• Description :

  This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia. [provided by RefSeq, Mar 2010],

• UniProt :

  Q7L5A8

• Swiss Prot :

  Q7L5A8

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from human FA2H. at AA range: 101-150

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, ELISA 1:10000-20000

• Molecular Weight :

  55kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  55kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .

• Other Product Names :

  Fatty acid 2-hydroxylase (EC 1.-.-.-) (Fatty acid alpha-hydroxylase)

• Gene ID (Human) :

  79152