Granzyme M rabbit pAb

CAT: 0855-ES8807-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES8807-01Size:50 µL
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Background
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Description
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
UniProt
P51124
Swiss Prot
P51124
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 207-256
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
Other Product Names
Granzyme M (EC 3.4.21.-; Met-1 serine protease; Hu-Met-1; Met-ase; Natural killer cell granular protease)
Gene ID (Human)
3004

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