Granzyme M rabbit pAb

• Background :

  Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Description :

  Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

• UniProt :

  P51124

• Swiss Prot :

  P51124

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthetic peptide from human protein at AA range: 207-256

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.

• Other Product Names :

  Granzyme M (EC 3.4.21.-; Met-1 serine protease; Hu-Met-1; Met-ase; Natural killer cell granular protease)

• Gene ID (Human) :

  3004