Granzyme B rabbit pAb
CAT:
855-ES8917-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Granzyme B rabbit pAb
- Description: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],
- Synonyms: Granzyme B (EC 3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E)
- Gene ID: 3002
- UniProt: P10144
- Cellular Locus: Secreted. Cytolytic granule. Delivered into the target cell by perforin (PubMed:20038786)..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from human Granzyme B Polyclonal AA range: 81-130
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
- Molecular Weight: 38kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.