Granzyme A rabbit pAb

CAT:

855-ES5709-01

Size:

50 μL

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Description: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008],
Synonyms: GZMA; CTLA3; HFSP; Granzyme A; CTL tryptase; Cytotoxic T-lymphocyte proteinase 1; Fragmentin-1; Granzyme-1; Hanukkah factor; H factor; HF
Gene ID: 3001
UniProt: P12544
Cellular Locus: [Isoform alpha]: Secreted. Cytoplasmic granule. Delivered into the target cell by perforin..
Host: Rabbit
Species Reactivity: Human, Rat, Mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human GRAA. AA range:61-110
Clonality: Polyclonal
Validated Applications: IHC, IF, ELISA
Stability: 1 year
Concentration: 1 mg/mL
Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.