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CD231 rabbit pAb

CAT: 0855-ES8698-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8698-02Size:100 µL
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Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008],
UniProt
P41732
Swiss Prot
P41732
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 101-150
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Other Product Names
Tetraspanin-7 (Tspan-7; Cell surface glycoprotein A15; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; Transmembrane 4 superfamily member 2; CD antigen CD231)
Gene ID (Human)
7102

UniProtKB · P41732

Tetraspanin-7

TSN7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P41732
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TSPAN7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Tspan-7
EC number
—
Processing
—
Secondary accessions
B2R5W7, D3DWB1, Q8WVG5, Q9UEY9
Protein keywords

Disease

Disease variantIntellectual disability

PTM

Glycoprotein

Biological process

Host-virus interaction

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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