CD236 rabbit pAb

• Background:

  Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

• Description:

  Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012],

• UniProt:

  P04921

• Swiss Prot:

  P04921

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthetic peptide from human protein at AA range: 11-60

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane; Single-pass type III membrane protein. Linked to the membrane via band 4.1.

• Other Product Names:

  Glycophorin-C (Glycoconnectin; Glycophorin-D; GPD; Glycoprotein beta; PAS-2'; Sialoglycoprotein D; CD antigen CD236)

• Gene ID (Human):

  2995