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FAM48A rabbit pAb

CAT: 0855-ES8546-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8546-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail., similarity:Belongs to the FAM48 family., subunit:Interacts with MAPK14., tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
Description
Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. similarity: Belongs to the FAM48 family. subunit: Interacts with MAPK14. tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
Product Name Alternative
FAM48A C13orf19 FP757
UniProt
Q8NEM7
Swiss Prot
Q8NEM7
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280
Target
FAM48A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
FAM48A C13orf19 FP757
Gene ID (Human)
55578

UniProtKB · Q8NEM7

Transcription factor SPT20 homolog

SP20H_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NEM7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SUPT20H
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E7ER46, Q71RF3, Q9Y6A6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AutophagyGastrulation

Molecular function

Developmental protein

Cellular component

Nucleus

PTM

Phosphoprotein

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