ICOS rabbit pAb

• Background:

  The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008],

• UniProt:

  Q9Y6W8

• Swiss Prot:

  Q9Y6W8

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human ICOS. AA range:31-80

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  22kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  22kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .

• Other Product Names:

  ICOS; AILIM; Inducible T-cell costimulator; Activation-inducible lymphocyte immunomediatory molecule; CD278

• Gene ID (Human):

  29851