ICOS Rabbit Monoclonal Antibody

• Background:

  Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells.

• Product Name Alternative:

  AILIM; CD278; CRP1; CVID1; ICOS; ; ICOS

• Gene Name:

  ICOS

• Swiss Prot:

  Q9Y6W8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, ICC, FC

• Purification:

  Affinity Purification

• Dilution:

  WB 1:1000-1:2000, ICC 1:50-1:200, FC 1:20-1:100

• Form:

  Liquid

• Buffer:

  Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 23 kDa ; Observed MW: 22 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG