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RUFY1 rabbit pAb

CAT: 0855-ES7614-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7614-01Size:50 µL
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Background
RUN and FYVE domain containing 1 (RUFY1) Homo sapiens This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Description
RUN and FYVE domain containing 1 (RUFY1) Homo sapiens This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Product Name Alternative
RUFY1; RABIP4; ZFYVE12; RUN and FYVE domain-containing protein 1; FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; Zinc finger FYVE domain-containing protein 12
UniProt
Q96T51
Swiss Prot
Q96T51
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RUFY1. AA range:139-188
Target
RUFY1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Other Product Names
RUFY1; RABIP4; ZFYVE12; RUN and FYVE domain-containing protein 1; FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; Zinc finger FYVE domain-containing protein 12
Gene ID (Human)
80230

UniProtKB · Q96T51

RUN and FYVE domain-containing protein 1

RUFY1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96T51
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RUFY1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q59FF3, Q71S93, Q9H6I3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilZinc-finger

Biological process

EndocytosisProtein transportTransport

Cellular component

EndosomeMembrane

Ligand

Lipid-bindingMetal-bindingZinc

PTM

Phosphoprotein

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