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Vitronectin rabbit pAb

CAT: 0855-ES7512-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7512-02Size:100 µL
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Background
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008],
Product Name Alternative
VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75
UniProt
P04004
Swiss Prot
P04004
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Vitronectin. AA range:209-258
Target
Vitronectin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space .; Parasitophorous vacuole . (Microbial infection) In P.falciparum-infected red blood cells, VTN internalization is detected at the early trophozoite stage (PubMed:29567995) . Colocalizes with SERA5 at the schizont stage and with SERA5 P47 at the merozoite surface (PubMed:29567995) . .
Other Product Names
VTN; Vitronectin; VN; S-protein; Serum-spreading factor; V75
Gene ID (Human)
7448

UniProtKB · P04004

Vitronectin

VTNC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04004
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VTN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VN
EC number
—
Processing
Precursor
Secondary accessions
B2R7G0, P01141, Q9BSH7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell adhesion

PTM

Disulfide bondGlycoproteinPhosphoproteinSulfation

Molecular function

Heparin-binding

Domain

RepeatSignal

Cellular component

Secreted

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