Nicalin rabbit pAb
CAT:
855-ES6862-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nicalin rabbit pAb
- Description: Function: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. similarity: Belongs to the nicastrin family. subunit: Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex. tissue specificity: Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.
- Synonyms: NCLN; Nicalin; Nicastrin-like protein
- Gene ID: 56926
- UniProt: Q969V3
- Cellular Locus: Endoplasmic reticulum membrane ; Single-pass membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Molecular Weight: 63kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.