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Nicalin rabbit pAb

CAT: 0855-ES6862-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6862-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning., similarity:Belongs to the nicastrin family., subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex., tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.
Description
Function: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. similarity: Belongs to the nicastrin family. subunit: Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex. tissue specificity: Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.
UniProt
Q969V3
Swiss Prot
Q969V3
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
63kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
63kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein .
Other Product Names
NCLN; Nicalin; Nicastrin-like protein
Gene ID (Human)
56926

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Alternative Products

CatalogName
E47R11594Nicalin Rabbit pAb
APRab14693-01Nicalin Rabbit Polyclonal Antibody
NBP3-18435Rabbit Polyclonal Nicalin Antibody
SL11594R-01Rabbit Anti-Nicalin antibody
NBP2-81860BRabbit Polyclonal Nicalin Antibody [Biotin]
NBP2-81860HRabbit Polyclonal Nicalin Antibody [HRP]
NBP2-81860PCPRabbit Polyclonal Nicalin Antibody [PerCP]
NBP2-81860FRabbit Polyclonal Nicalin Antibody [FITC]
NBP3-18435CRabbit Polyclonal Nicalin Antibody [DyLight 650]
NBP3-18435RRabbit Polyclonal Nicalin Antibody [DyLight 550]

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