CD205 rabbit pAb

CAT: 0855-ES6143-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES6143-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity) . Causes reduced proliferation of B-lymphocytes., miscellaneous:Isoform 2 and isoform 3 are produced in HRS cells by a transcriptional control mechanism which cotranscribe an mRNA containing LY75 and CD302 prior to generating the intergenically spliced mRNA to produce LY75/CD302 fusion proteins., online information:DEC-205, PTM:N-glycosylated., similarity:Contains 1 C-type lectin domain., similarity:Contains 1 fibronectin type-II domain., similarity:Contains 1 ricin B-type lectin domain., similarity:Contains 10 C-type lectin domains., tissue specificity:Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells., tissue specificity:Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells.
Description
Function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes. miscellaneous: Isoform 2 and isoform 3 are produced in HRS cells by a transcriptional control mechanism which cotranscribe an mRNA containing LY75 and CD302 prior to generating the intergenically spliced mRNA to produce LY75/CD302 fusion proteins. online information: DEC-205, PTM: N-glycosylated. similarity: Contains 1 C-type lectin domain. similarity: Contains 1 fibronectin type-II domain. similarity: Contains 1 ricin B-type lectin domain. similarity: Contains 10 C-type lectin domains. tissue specificity: Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells. tissue specificity: Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin's lymphoma cells called Hodgkin's and Reed-Sternberg (HRS) cells.
Product Name Alternative
LY75; CD205; CLEC13B; Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD antigen CD205
UniProt
O60449
Swiss Prot
O60449
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CD205.
Target
CD205
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
200kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
200kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Other Product Names
LY75; CD205; CLEC13B; Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD antigen CD205
Gene ID (Human)
4065

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