LARG rabbit pAb
CAT:
855-ES5333-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
LARG rabbit pAb
- Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
- Synonyms: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
- Gene ID: 23365
- UniProt: Q9NZN5
- Cellular Locus: Cytoplasm. Membrane. Translocated to the membrane upon stimulation..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Molecular Weight: 173kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.