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ARX rabbit pAb

CAT: 0855-ES4997-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4997-02Size:100 µL
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Background
This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy. [provided by RefSeq, Jul 2016]
Description
This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy. [provided by RefSeq, Jul 2016],
Product Name Alternative
ARX; Homeobox protein ARX; Aristaless-related homeobox
UniProt
Q96QS3
Swiss Prot
Q96QS3
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from ARX . at AA range: 250-330
Target
ARX
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
ARX; Homeobox protein ARX; Aristaless-related homeobox
Gene ID (Human)
170302

UniProtKB · Q96QS3

Homeobox protein ARX

ARX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96QS3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ARX
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Cellular component

ChromosomeNucleus

Molecular function

Developmental proteinDNA-binding

Biological process

DifferentiationNeurogenesisTranscriptionTranscription regulation

Disease

Disease variantEpilepsyIntellectual disabilityLissencephaly

Domain

Homeobox

Technical term

Proteomics identificationReference proteome

Coding sequence diversity

Triplet repeat expansion

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