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DD1 rabbit pAb

CAT: 0855-ES4978-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4978-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008],
UniProt
Q04828
Swiss Prot
Q04828
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from DD1 . at AA range: 30-110
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol .
Other Product Names
AKR1C1; DDH; DDH1; Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1/2; DD1/DD2; High-affinity hepatic bile acid-binding protein; HB
Gene ID (Human)
1645

UniProtKB · Q04828

Aldo-keto reductase family 1 member C1

AK1C1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04828
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AKR1C1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.1.1.-, 1.1.1.112, 1.1.1.209, 1.1.1.210, 1.1.1.357, 1.1.1.51, 1.1.1.53, 1.1.1.62, 1.3.1.20
Processing
—
Secondary accessions
P52896, Q5SR15, Q7M4N2, Q9UCX2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cytoplasm

Biological process

Lipid metabolism

Ligand

NADP

Molecular function

Oxidoreductase

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