COL4A5 rabbit pAb

• Background:

  This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]

• Description:

  This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010],

• UniProt:

  P29400

• Swiss Prot:

  P29400

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human Collagen IV alpha5. AA range:21-70

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  160kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  160kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted, extracellular space, extracellular matrix, basement membrane.

• Other Product Names:

  COL4A5; Collagen alpha-5 (IV) chain

• Gene ID (Human):

  1287