PHAPI2 rabbit pAb

• Background:

  Function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity., similarity:Belongs to the ANP32 family., similarity:Contains 4 LRR (leucine-rich) repeats., subcellular location:Accumulates in the nuclei at the S phase., tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

• Description:

  Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. similarity: Belongs to the ANP32 family. similarity: Contains 4 LRR (leucine-rich) repeats. subcellular location: Accumulates in the nuclei at the S phase. tissue specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

• Synonyms:

  ANP32B; APRIL; PHAPI2; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29

• Gene ID:

  10541

• UniProt:

  Q92688

• Cellular Locus:

  [Isoform 1]: Nucleus. Cytoplasm. Accumulates in the nuclei at the S phase..; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA, IHC

• Validated Applications:

  WB, ELISA, IHC

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight:

  29kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  29 kD

• Subcellular Location:

  [Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.

• Other Product Names:

  ANP32B; APRIL; PHAPI2; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29

• Gene ID (Human):

  10541

• SwissProt (Human):

  Q92688