TOB1 rabbit pAb

• Background:

  This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

• Description:

  This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],

• Synonyms:

  TOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1

• Gene ID:

  10140

• UniProt:

  P50616

• Cellular Locus:

  Cytoplasm. Nucleus. Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TOB1. AA range:130-179

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  40kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  40 kD

• Subcellular Location:

  Cytoplasm . Nucleus . Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. .

• Other Product Names:

  TOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1

• Gene ID (Human):

  10140

• SwissProt (Human):

  P50616