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ZIS rabbit pAb

CAT: 0855-ES3732-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3732-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The RanBP2-type zinc fingers mediate binding to RNA., function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection., PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR., sequence caution:Intron retention., similarity:Belongs to the ZRANB2 family., similarity:Contains 2 RanBP2-type zinc fingers., subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.
Description
Domain: The RanBP2-type zinc fingers mediate binding to RNA. function: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection. PTM: Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR. sequence Caution: Intron retention. similarity: Belongs to the ZRANB2 family. similarity: Contains 2 RanBP2-type zinc fingers. subunit: Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.
Product Name Alternative
ZRANB2; ZIS; ZNF265; Zinc finger Ran-binding domain-containing protein 2; Zinc finger protein 265; Zinc finger; splicing
UniProt
O95218
Swiss Prot
O95218
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF265. AA range:106-155
Target
ZIS
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
34kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
34kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
ZRANB2; ZIS; ZNF265; Zinc finger Ran-binding domain-containing protein 2; Zinc finger protein 265; Zinc finger; splicing
Gene ID (Human)
9406

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