RORγ rabbit pAb

• Background:

  The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• UniProt:

  P51449

• Swiss Prot:

  P51449

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human RORG. AA range:71-120

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight:

  58kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  58kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus .

• Other Product Names:

  RORC; NR1F3; RORG; RZRG; Nuclear receptor ROR-gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; Retinoid-related orphan receptor-gamma

• Gene ID (Human):

  6097