RORγ rabbit pAb

CAT: 0855-ES3390-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3390-01Size:50 µL
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Background
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
UniProt
P51449
Swiss Prot
P51449
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RORG. AA range:71-120
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
RORC; NR1F3; RORG; RZRG; Nuclear receptor ROR-gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; Retinoid-related orphan receptor-gamma
Gene ID (Human)
6097

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