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PHyde rabbit pAb

CAT: 0855-ES3196-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3196-02Size:100 µL
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Background
STEAP3 metalloreductase (STEAP3) Homo sapiens This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Description
STEAP3 metalloreductase (STEAP3) Homo sapiens This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
Product Name Alternative
STEAP3; TSAP6; Metalloreductase STEAP3; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde
UniProt
Q658P3
Swiss Prot
Q658P3
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human STEA3. AA range:421-470
Target
PHyde
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
54kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
54kD
Fragment
IgG
Subcellular Location
Endosome membrane ; Multi-pass membrane protein . Localizes to vesicular-like structures at the plasma membrane and around the nucleus.
Other Product Names
STEAP3; TSAP6; Metalloreductase STEAP3; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHyde
Gene ID (Human)
55240

UniProtKB · Q658P3

Metalloreductase STEAP3

STEA3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q658P3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
STEAP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.16.1.-
Processing
—
Secondary accessions
A8K6E3, Q4VBR2, Q4ZG36, Q53SQ8, Q7Z389, Q86SF6, Q8NEW6, Q8TDP3, Q8TF03, Q9NVB5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCell cycleIon transportIron transportTransport

Ligand

CopperFADFlavoproteinHemeIronMetal-bindingNADP

Cellular component

EndosomeMembrane

PTM

GlycoproteinPhosphoprotein

Molecular function

Oxidoreductase

Domain

TransmembraneTransmembrane helix

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