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Musculin rabbit pAb

CAT: 0855-ES2869-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2869-01Size:50 µL
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Background
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008],
UniProt
O60682
Swiss Prot
O60682
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Musculin. AA range:131-180
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
22kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
22kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
MSC; ABF1; BHLHA22; Musculin; Activated B-cell factor 1; ABF-1; Class A basic helix-loop-helix protein 22; bHLHa22
Gene ID (Human)
9242

UniProtKB · O60682

Musculin

MUSC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60682
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MSC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O75946, Q53XZ2, Q9BRE7
Protein keywords

Molecular function

DNA-bindingRepressor

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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