MLH1 rabbit pAb
CAT:
855-ES2797-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MLH1 rabbit pAb
- Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009],
- Synonyms: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
- Gene ID: 4292
- UniProt: P40692
- Cellular Locus: Nucleus. Chromosome. Recruited to chromatin in a MCM9-dependent manner..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490
- Clonality: Polyclonal
- Validated Applications: WB, IHC
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000;IHC-p 1:50-300
- Molecular Weight: 85kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.