DF 461

CAT:

804-HY-16620

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CAS Number: 937051-40-6
UNSPSC Description: DF 461 is a sterol synthase inhibitor with significant inhibitory activity. DF 461 shows high selectivity for the liver and can effectively inhibit cholesterol synthesis in rat liver. DF 461 has shown the effect of lowering plasma lipids in repeated dosing studies in non-rodents[1].
Target Antigen: Endogenous Metabolite
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Field of Research: Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/df-461.html
Smiles: O=C(O)C[C@@H]1C2=NN=C(C(F)(F)F)N2C3=CC=C(Cl)C=C3[C@@H](C4=CC=CC(OC)=C4Cl)O1
Molecular Weight: 488.24
References & Citations: [1]Discovery of DF-461, a Potent Squalene Synthase Inhibitor
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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