Ganoderic acid Df

• Description:

  Ganoderic acid Df is a lanostane-type triterpenoid, that can be isolated from the fruiting body of Ganoderma lucidum. Ganoderic acid Df potently inhibits aldose reductase, with an IC50 of 22.8 ± 0.6 μM[1].

• UNSPSC:

  12352211

• Target:

  Aldose Reductase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ganoderic-acid-df.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12C3=C([C@H](C[C@@]1([C@@](CC2=O)([H])[C@H](C)CC(CC(C)C(O)=O)=O)C)O)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])C[C@@H]3O)C

• Molecular Formula:

  C30H44O7

• Molecular Weight:

  516.67

• References & Citations:

  [1]Fatmawati S, et al. Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum. Fitoterapia. 2010 Dec;81 (8) :1033-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  1352033-73-8