Products for Research Use Only

LASS4 rabbit pAb

CAT: 0855-ES2701-02Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2701-02Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Function:May be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner., similarity:Contains 1 homeobox DNA-binding domain., similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Description
Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner. similarity: Contains 1 homeobox DNA-binding domain. similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain.
UniProt
Q9HA82
Swiss Prot
Q9HA82
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Other Product Names
CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4
Gene ID (Human)
79603

UniProtKB · Q9HA82

Ceramide synthase 4

CERS4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HA82
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CERS4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CerS4
EC number
2.3.1.-
Processing
—
Secondary accessions
D6W665
Protein keywords

Cellular component

Endoplasmic reticulumMembrane

PTM

GlycoproteinPhosphoprotein

Biological process

Lipid biosynthesisLipid metabolism

Technical term

Proteomics identificationReference proteome

Molecular function

Transferase

Domain

TransmembraneTransmembrane helix