LASS4 rabbit pAb

• Background:

  Function:May be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner., similarity:Contains 1 homeobox DNA-binding domain., similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.

• Description:

  Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner. similarity: Contains 1 homeobox DNA-binding domain. similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain.

• Synonyms:

  CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4

• Gene ID:

  79603

• UniProt:

  Q9HA82

• Cellular Locus:

  Endoplasmic reticulum membrane ; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  46kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  46 kD

• Subcellular Location:

  Endoplasmic reticulum membrane ; Multi-pass membrane protein .

• Other Product Names:

  CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4

• Gene ID (Human):

  79603

• SwissProt (Human):

  Q9HA82