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Connexin 25 rabbit pAb

CAT: 0855-ES2027-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2027-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]) .[supplied by OMIM, Mar 2008]
Description
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al. 2003 [PubMed 12881038]). [supplied by OMIM, Mar 2008],
Product Name Alternative
GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25
UniProt
Q6PEY0
Swiss Prot
Q6PEY0
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70
Target
Connexin 25
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
Other Product Names
GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25
Gene ID (Human)
375519

UniProtKB · Q6PEY0

Gap junction beta-7 protein

CXB7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6PEY0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GJB7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KXL0, Q96KP0
Protein keywords

Cellular component

Cell junctionCell membraneGap junctionMembrane

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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