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Connexin-26 Rabbit pAb

CAT: 0855-EA280-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EA280-01Size:50 µL
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Background
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Description
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Product Name Alternative
GJB2, CX26, DFNA3, DFNB1, HID, NSRD1, PPK
UniProt
P29033
Swiss Prot
P29033
Reactivity
Human, Mouse
Immunogen
Synthetic Peptide
Clonality
Polyclonal
Source
Rabbit
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
26kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
26kDa
Fragment
IgG
Subcellular Location
Cell junction, Cell membrane, Gap junction, Membrane
Other Product Names
GJB2, CX26, DFNA3, DFNB1, HID, NSRD1, PPK
Gene ID (Human)
2706

UniProtKB · P29033

Gap junction beta-2 protein

CXB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P29033
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GJB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q508A5, Q508A6, Q5YLL0, Q5YLL1, Q5YLL4, Q6IPV5, Q86U88, Q96AK0, Q9H536, Q9NNY4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMetal-binding

Cellular component

Cell junctionCell membraneGap junctionMembrane

Disease

DeafnessDisease variantEctodermal dysplasiaIchthyosisNon-syndromic deafnessPalmoplantar keratoderma

PTM

Disulfide bond

Biological process

Hearing

Domain

TransmembraneTransmembrane helix

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