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GABA B Receptor 2 Rabbit pAb

CAT: 0855-EA288-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EA288-01Size:50 µL
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Background
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Description
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Product Name Alternative
GABBR2, Gamma aminobutyric acid B receptor 2, GB2, HG20
UniProt
O75899
Swiss Prot
O75899
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Polyclonal
Source
Rabbit
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
106kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
106kDa
Fragment
IgG
Subcellular Location
Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse
Other Product Names
GABBR2, Gamma aminobutyric acid B receptor 2, GB2, HG20
Gene ID (Human)
9568

UniProtKB · O75899

Gamma-aminobutyric acid type B receptor subunit 2

GABR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75899
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GABBR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2
EC number
—
Processing
Precursor
Secondary accessions
O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

Domain

Coiled coilSignalTransmembraneTransmembrane helix

Disease

Disease variantEpilepsyIntellectual disability

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

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