GABA A Receptor γ2 rabbit pAb

• Background:

  This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Description:

  This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

• UniProt:

  P18507

• Swiss Prot:

  P18507

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthetic Peptide of GABA A Receptor γ2

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:1000-2000, IHC 1:100-200

• Molecular Weight:

  55kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  55kD

• Fragment:

  IgG

• Subcellular Location:

  Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cytoplasmic vesicle membrane .

• Other Product Names:

  Gamma-aminobutyric acid receptor subunit gamma-2 (GABA (A) receptor subunit gamma-2)

• Gene ID (Human):

  2566