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GABA A Receptor α2 Rabbit pAb

CAT: 0855-EA285-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EA285-01Size:50 µL
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Background
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Description
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Product Name Alternative
GABA, GABRA2, GBRA2, GABA A receptor subunit alpha 2
UniProt
P47869
Swiss Prot
P47869
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Polyclonal
Source
Rabbit
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
51kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
51kDa
Fragment
IgG
Subcellular Location
Cell junction, Cell membrane, Cytoplasmic vesicle, Membrane, Postsynaptic cell membrane, Synapse
Other Product Names
GABA, GABRA2, GBRA2, GABA A receptor subunit alpha 2
Gene ID (Human)
282236

UniProtKB · P47869

Gamma-aminobutyric acid receptor subunit alpha-2

GBRA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P47869
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GABRA2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K0U7, B7Z1H8, Q59G14
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionCytoplasmic vesicleMembranePostsynaptic cell membraneSynapse

Ligand

Chloride

Molecular function

Chloride channelIon channelLigand-gated ion channelReceptor

Disease

Disease variantEpilepsy

PTM

Disulfide bondGlycoprotein

Biological process

Ion transportTransport

Domain

SignalTransmembraneTransmembrane helix

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