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EAAT2 Rabbit pAb

CAT: 0855-EA284-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-EA284-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Excitatory amino acid transporters (EAATs) regulate and maintain extracellular glutamate concentrations below excitotoxic levels. In addition, glutamate transporters may limit the duration of synaptic excitation by an electrogenic process in which the transmitter is cotransported with three sodium ions and one proton, followed by countertransport of a potassium ion.
Description
Excitatory amino acid transporters (EAATs) regulate and maintain extracellular glutamate concentrations below excitotoxic levels. In addition, glutamate transporters may limit the duration of synaptic excitation by an electrogenic process in which the transmitter is cotransported with three sodium ions and one proton, followed by countertransport of a potassium ion.
Product Name Alternative
Excitatory amino acid transporter 2, Slcla2, GLT1
UniProt
P43004
Swiss Prot
P43004
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
62kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
62kDa
Fragment
IgG
Subcellular Location
Membrane
Other Product Names
Excitatory amino acid transporter 2, Slcla2, GLT1
Gene ID (Human)
6506

UniProtKB · P43004

Excitatory amino acid transporter 2

EAA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P43004
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC1A2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DQE9, Q14417, Q541G6, U3KQQ4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Amino-acid transportSymportTransport

Cellular component

Cell membraneMembrane

Ligand

ChlorideMetal-bindingPotassiumSodium

Disease

Disease variantEpilepsy

PTM

GlycoproteinLipoproteinPalmitatePhosphoprotein

Domain

TransmembraneTransmembrane helix

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