LC3A (5G10) Mouse mAb

• Background:

  Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

• Description:

  Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

• Synonyms:

  ATG8E, MAP1LC3A, autophage-related protein LC3A

• Gene ID:

  84557

• UniProt:

  Q9H492

• Cellular Locus:

  Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Microtubule

• Host:

  Mouse

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Source:

  Mouse

• Applications:

  WB, IHC

• Validated Applications:

  WB, IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:100-200

• Molecular Weight:

  14,16kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  14,16 kDa

• Subcellular Location:

  Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Microtubule

• Other Product Names:

  ATG8E, MAP1LC3A, autophage-related protein LC3A

• Gene ID (Human):

  84557

• SwissProt (Human):

  Q9H492