RegisterLogin

CD68 Mouse mAb

CAT: 0855-EM1162-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-EM1162-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Description
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Product Name Alternative
CD68 molecule, GP110, Macrosialin, SCARD1
UniProt
P34810
Swiss Prot
P34810
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:200-500
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Fragment
IgG1
Subcellular Location
Cell membrane and Endosome membrane. Lysosome membrane
Other Product Names
CD68 molecule, GP110, Macrosialin, SCARD1
Gene ID (Human)
968

Related Products

CatalogName
ES3940-01CD68 rabbit pAb
EM1107-01CD25 Mouse mAb
EM1197-01TNF α Mouse mAb
EM1181-01GAP43 Mouse mAb
EM1185-01CREB Mouse mAb
EM1200-01HSC70 Mouse mAb
EM1052-01P53 Mouse mAb
EM1056-01CK16 Mouse mAb
EM1161-01Lactoferrin Mouse mAb
EM1085-01EFHD1 Mouse mAb

Alternative Products

CatalogName
E2252670CD68 (ABT-CD68) Mouse mAb
YP-W20042-01Mouse CD68 (CD68) ELISA Kit
E11-126022CD68 (Clone ENG-CD68) Mouse mAb
E2221108CD68 Mouse mAb
GWB-Q01477Mouse CD68 Antibody
RM680020Anti-Mouse CD68
15561054CD68 Adenovirus (Mouse)
MBS767724-01CD68 Mouse Monoclonal
UB-GEN-16731CD68 (ABT-CD68) mouse mAb Ready to use
NBP3-11551Mouse Monoclonal CD68/SR-D1 Antibody (CD68/G2)

Popular Products