P53 Mouse mAb

• Background:

  P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.

• Description:

  P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.

• UniProt:

  P04637

• Swiss Prot:

  P04637

• Reactivity:

  Human

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB, IHC, IF

• Concentration:

  1mg/mL

• Dilution:

  WB 1:2,000 IHC 1:200 IF 1:100-200

• Molecular Weight:

  53kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  53kDa

• Fragment:

  IgG1

• Subcellular Location:

  Cytoplasm; Cytoplasm. Nucleus

• Other Product Names:

  Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53

• Gene ID (Human):

  7157