RORγt inverse agonist 26

• UNSPSC Description:

  RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) [1].

• Target Antigen:

  ROR

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rorγt-inverse-agonist-26.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(C=C(C=C1)C(C(F)(F)F)(O)C(F)(F)F)=C1C(C=C2)=CC=C2NC([C@H]3C4=CC=C(S(C)(=O)=O)C=C4CN3C(C)=O)=O

• Molecular Weight:

  618.52

• References & Citations:

  [1]Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2738333-10-1