RORγt inverse agonist 26

RORγt inverse agonist 26

• CAS Number: 2738333-10-1
• UNSPSC Description: RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) [1].
• Target Antigen: ROR
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/rorγt-inverse-agonist-26.html
• Solubility: 10 mM in DMSO
• Smiles: FC(C=C(C=C1)C(C(F)(F)F)(O)C(F)(F)F)=C1C(C=C2)=CC=C2NC([C@H]3C4=CC=C(S(C)(=O)=O)C=C4CN3C(C)=O)=O
• Molecular Weight: 618.52
• References & Citations: [1]Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported