MI-nc (hydrochloride)
CAT:
26-B2816-5
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MI-nc (hydrochloride)
- Description: MI-nc (hydrochloride) is a weak inhibitor of the menin-MLL interaction. Menin is a tumor suppressor protein. Menin is a part of the MLL (Mixed Lineage Leukemia) SET1-like histone methyl transferase complex. Association of menin with MLL fusion proteins causes oncogenic transformation. MI-nc (hydrochloride) showed very weak inhibition of the menin-MLL interaction (IC₅₀ = 193 μM) in vitro. It serves as a negative control for MI-2 which is a potent menin-MLL interaction inhibitor (IC₅₀ = 0.45 μM).
- Shipping Conditions: RT
- Storage Conditions: -20ºC
- Shelf Life: 36 months