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MI-nc (hydrochloride)

CAT: 0026-B2816-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2816-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MI-nc (hydrochloride) is a weak inhibitor of the menin-MLL interaction. Menin is a tumor suppressor protein. Menin is a part of the MLL (Mixed Lineage Leukemia) SET1-like histone methyl transferase complex. Association of menin with MLL fusion proteins causes oncogenic transformation. MI-nc (hydrochloride) showed very weak inhibition of the menin-MLL interaction (IC₅₀ = 193 μM) in vitro. It serves as a negative control for MI-2 which is a potent menin-MLL interaction inhibitor (IC₅₀ = 0.45 μM).
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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