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MALT1 Inhibitor, MI-2

CAT: 0026-B2368-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2368-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MALT1 inhibitor MI-2 is a potent inhibitor of the paracaspase MALT1 (Mucosa-associated-lymphoid-tissue lymphoma-translocation gene 1) (IC₅₀ = 5.84 μM). MI-2 binds directly to MALT1 and irreversibly suppresses protease function. Inhibits cell proliferation and MALT1-mediated cleavage activity. Suppresses human TMD8 and HBL-1 activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) tumor xenografts in mice and primary human ABC-DLBCLs ex vivo.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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