Hydroxy-Epsilon-Sanshool

• Description:

  Hydroxy-Epsilon-Sanshool is an alkylamide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensates, and its content is important in determinant the pungency intensity of Zanthoxylum bungeanum[1][2].

• UNSPSC:

  12352211

• Target:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-epsilon-sanshool.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/C=C\C=C\C=C/CC/C=C/C(NCC(C)(O)C)=O

• Molecular Formula:

  C16H25NO2

• Molecular Weight:

  263.38

• References & Citations:

  [1]Zhang LL, et al. The relationship between alkylamide compound content and pungency intensity of Zanthoxylum bungeanum based on sensory evaluation and ultra-performance liquid chromatography-mass spectrometry/ mass spectrometry (UPLC-MS/MS) analysis. J Sci Food Agric. 2019 Mar 15;99 (4) :1475-1483.|[2]Bader M, et al. All-trans-configuration in Zanthoxylum alkylamides swaps the tingling with a numbing sensation and diminishes salivation. J Agric Food Chem. 2014 Mar 26;62 (12) :2479-88.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [252193-26-3]