Hydroxy-α-sanshool (Standard)

• Description:

  Hydroxy-α-sanshool (Standard) is the analytical standard of Hydroxy-α-sanshool. This product is intended for research and analytical applications. Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 μM, respectively. Hydroxy-α-sanshool can be used for pain research[1][2].

• UNSPSC:

  12352211

• Target:

  Endogenous Metabolite; Reference Standards; TRP Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-α-sanshool-standard.html

• Smiles:

  C/C=C/C=C/C=C\CC/C=C/C (NCC (C) (O) C) =O

• Molecular Formula:

  C16H25NO2

• Molecular Weight:

  263.38

• References & Citations:

  [1]Koo JY, et al. Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol. 2009 Aug;157 (8) :1398-409.|[2]Koo JY, et al. Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. Eur J Neurosci. 2007 Sep;26 (5) :1139-47.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  83883-10-7