γ-Sanshool

• Description :

  γ-Sanshool can be isolated from Zanthoxylum piperitum. γ-Sanshool inhibits human ACAT-1 and ACAT-2 activities with IC50s of 12.0 and 82.6 μM[1].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Acyltransferase

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/γ-sanshool.html

• Purity :

  99.23

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  C/C=C/C=C/C=C\CC/C=C/C=C/C(NCC(C)C)=O

• Molecular Formula :

  C18H27NO

• Molecular Weight :

  273.41

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Park YD, et al. Human acyl-CoA: cholesterol acyltransferase inhibitory activities of aliphatic acid amides from Zanthoxylum piperitum DC. Biol Pharm Bull. 2007 Jan;30 (1) :205-7.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C, stored under nitrogen

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [78886-65-4]